Thursday, 2 April 2015

Grow Your Own Heart.



Sri Husband read aloud: “A young Captain of the Indian Army… bullet damaged his spine,… was doomed to paralyses waist downwards for life… two years after that injury, last week he walked. Thanks to stem-cell treatment.”
“Miracle,” I supposed. “Which god did he pray to?”
Sri Husband googled rapidly: “Stem-cell treatment is … the result of decades of focused and fantastic research. After antibiotics, stem-cell therapy is THE breakthrough in medical science. In recent decades, the Nobel Prize for medicine has gone to those who have done research in cell-related studies… tissues, organs, even limbs can be grown by using this method.”
Limbs being grown? Like lizards’ tails?
I bent forward to check. He wasn’t inventing the stuff. “Stem-cells are unspecialized cells which can be got from a placenta during childbirth or from an embryo. Stem-cell therapy is still in the experimental stage, but for those who are paralyzed or with a failed organ, the only hope. ”
Sri Husband, cynical as ever: “There’s a gap between hype and hope.”
I read on: “The single-cell female ‘egg’/ovum is potentially able to become any tissue or organ. A fertilized ovum starts to multiply rapidly and at different stages is known by names like blastula, gastrula and, later, foetus. During these stages, the cells become ‘specialized’. Either they become skin and bone (ectoderm) or nerves, brain, muscle (mesoderm) or stomach, liver, etc (endoderm). Once their roles are known, they have a fixed life-cycle, they fulfil their duties and die, to be replaced by others. If one has to grow cells for stem-cell treatment, we have to catch ‘em ‘young’ at a stage when they are still not ‘specialized’.”
Sri Husband: “As of now no factories involved.
Stem-cells are harvested. The nucleus from a stem-cell is put it into a patient’s kidney or heart-muscle and technology does its magic.”
Me: “Busss. So that’s how it’s done.”
“I’m sure it’s much more complicated than busss.” Sri Husband, irritated.  
Me: “Some parents are preparing for their children’s future illnesses. They’re storing/freezing their children’s placenta cells.”
Sri Husband: “I guess those who have terrible hereditary conditions would do anything to spare their offspring the agony.”
Me: “There are people who have stored ‘spare’ embryos also.”
Sri Husband at his fault-finding best: “For how long can such embryos stay ‘live’? Or stem-cells? If thawed after a couple of years, will they be as effective? If many remain unused, stem-cell banks will overflow. The embryos can’t be stored forever. Who will give consent to destroy them? Who knows what complications might happen arise after many years?”
Me: “People can ask questions. What are the risks? People should ask. Like in bone-marrow transplantation and other expensive procedures, they ask, is the doctor or institution licenced for the treatment? They meet other patients who were treated. People get in writing what the costs are and what they include. People are smart.”   
It seems there are companies selling (like one would sell drugs or any medicinal products) processed stem-cells for skin and some other ailments. They are useful for bad burn cases, I read somewhere.
Sri Husband asked: “What about the various legal, ethical, religious issues? How much time those discussions take! In-vitro fertilization (IVF) which has helped so many couples to have children has been around for years, and is still being debated. What if vulnerable patients (the poor, women, children, prisoners, the very old) get exploited for research in the name of science or progress? We know so little.”  
“Look,” I said. “Read this. ‘One can clone a person from stem-cells’. A clone is not a twin. Twins have their own sets of genes. A clone has a person’s exact gene combination. There can be two of me. It’s possible.”
Sri Husband snorted: “Nightmarish thought.”
I ignored that. “Only in theory.”
Sri Husband: “If anyone promises to clone you, ask all the questions you’ve just mentioned.”
He turned the newspaper and re-read about the young Captain who was paralyzed waist downwards “after an AK47 bullet ripped through him on September 25, 2012 and injured his vertebrae.”
“He’s a para-commando. He must have an incredible level of discipline, fitness and strength of mind. And a knowledgeable and supportive medical team at hand.”
Silence.
For once, Sri Husband and I were on the same page (literally, too): “The young Captain’s getting back to rigorous training.”
More silence.
His himmat had humbled us. One can grow a new heart, but how does one reproduce a zinda-dil insaan?
Feedback:sheelajaywant@yahoo.co.in

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